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Acetyl propionyl is not subject to the same legal regulations as diacetyl

In patients with diabetes among whom weight gain is a particular concern we saw the same pattern of a large risk reduction regardless of weight gained, noted Meigs, the senior author of the JAMA report

Similar results were also identified in lung epithelial cells exposed to various flavor additives such as acetoin (sweet and buttery), orthovanillin (vanilla), and cinnamaldehyde (cinnamon), which exhibited an increase in proinflammatory cytokines synthesis [59]

Additional co-authors include Julian Aviles, a statistician with the UCLA Center for Health Policy Research