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Les cellules pulmonaires saines remplacent progressivement les cellules endommages Afin dtudier les mutations des cellules pulmonaires causes par le tabac, les chercheurs lorigine de cette tude intitule Tobacco smoking and somatic mutations in human bronchial epithelium ont utilis comme mthode une biopsie des poumons de 16 personnes incluant des fumeurs, des anciens fumeurs, des non-fumeurs et des enfants

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Bronchial biopsies have demonstrated that marijuana users show not only manifest airway inflammation but also histopathological and/or molecular changes indicative of precancerous bronchial activity [50, 51]