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Since this was the mid-1960s, around 50 percent of adult men in the U.S

Call your doctor or dentist if you have: Unusually large sores Sores that spread Sores that last 2 weeks or longer Extreme pain despite avoiding trigger foods and taking over-the-counter pain medication Trouble drinking enough fluids A high fever with canker sores Frequent or lasting mouth sores, which may be a sign of problems such as a serious skin disorder called pemphigus, celiac disease, inflammatory bowel disease, Behcet's disease, an autoimmune disease, anemia, or HIV

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How the Pouch Feels & Tastes If the pouch appears unusual in texture, smell, or taste, avoid using it