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Characterization of root mucilage from melastoma malabathricum, with emphasis on its roles in aluminum accumulation

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Furthermore, the pharmacological inhibition of HDAC8 can effectively suppress p53 and p21 expressions and the phosphorylation of the cyclin-dependent kinase 2 (CDK2) induced by cisplatin to reduce the expression of pro-apoptotic genes, thus alleviating apoptosis and cell cycle arrest (Wang et al., 2024c)