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The ultimate intention is to safeguard the welfare and interest of the public against the threats and dangers of potentially addictive and harmful substances, such as synthetic cannabinoids, Valenzuela said

Lately, as also noted by the American Heart Association statement [211], hookah has been considered a global threatin partdue to the high increase of its use, in addition to the deleterious effects it has on human body such as frequent respiratory infections, persistent cough, oral and esophageal cancer, and induction of a pro-inflammatory state

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