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In addition, our results were still significant when we compared the non-age-matched groups, including younger patients who smoked marijuana and who presumably had less lifetime exposure to cigarette smoke. According to the CDC, 48.2 million people, or about 18% of Americans, used marijuana at least once in 2019

Beyond marijuana and tobacco smoke, irritants with the potential to induce spasms include pollen and dust

"It is not that those with reduced global brain volume tend to smoke from a genetic standpoint, but it is that those who smoke cause their brains to atrophy," he said