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(A similar drop in the incidence of cardiovascular events was seen in participants with diabetes but did not reach statistical significance, probably because less than 15 percent of the overall group was known to have diabetes.) We now can say without question that stopping smoking has a very positive effect on cardiovascular risk for patients with and without diabetes, even if they experience the moderate weight gain seen in this study, which matches post-cessation weight increase reported in other studies, said Meigs.