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Abbreviations AHR Adjusted hazard rate ASH Action on Smoking and Health AOR Adjusted odds ratio ARR Adjusted risk ratio CI Confidence interval COPD Chronic obstructive pulmonary disease EC Electronic cigarette eCO Expired carbon monoxide eNO Expired nitric oxide EPA Environmental Protection Agency HRCT High-resolution computed tomography NHIS National Health Interview Survey PATH Population Assessment of Tobacco and Health PICO Population, intervention, comparator, outcomes PRISMA Preferred Reported Items for Systematic Reviews and Meta-Analyses RCT Randomized controlled trial VERITAS Study The Vaping Effects: Real-World International Surveillance Study WHO World Health Organization Funding Open access funding provided by Universit degli Studi di Catania within the CRUI-CARE Agreement

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