Physical Injuries Falls Sports injuries Car accidents Stress injuries from repetitive motion (for example, carpal tunnel syndrome in the wrist) Vitamin Deficiencies Other nutritional deficiencies like vitamin B1, B6, E, and copper Medical Conditions Autoimmune diseases like multiple sclerosis (MS), lupus, and rheumatoid arthritis Kidney disease Liver disease Hormonal imbalances and thyroid disorders Rare autoimmune nerve diseases, like chronic inflammatory demyelinating polyneuropathy, in which the immune system attacks the myelin sheaths (protective fatty covering) of peripheral nerves Infections Human immunodeficiency virus (HIV) Other infections affecting nerves, like hepatitis C Medications and Toxic Substances Chemotherapy drugs used to treat cancer Alcohol misuse Exposure to toxins and heavy metals (lead, mercury, arsenic) Inherited Disorders Hereditary neuropathies like Charcot-Marie-Tooth disease can cause numbness, tingling, and other symptoms like foot deformities, thin calf muscles, and scoliosis (spine curvature) They can be diagnosed with tests such as genetic testing, nerve biopsy, and nerve condition studies

Environ Sci Pollut Res 25:54655473 Dobaradaran S, Soleimani F, Akhbarizadeh R, Schmidt TC, Marzban M, BasirianJahromi R (2021b) Environmental fate of cigarette butts and their toxicity in aquatic organisms: a comprehensive systematic review
The toxic effects of CO poisoning have been known for centuries
Let me tell you about Janie, a 47 year old woman who lives with her husband and her dog Queenie