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The study showed mechanistically that mtDNA released into the cytosol can bind to NLRP3, triggering its activation and the subsequent production of inflammatory cytokines like IL-1, contributing to inflammation in lung tissues (Nakahira et al., 2015) (Figure 2)

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"Although the government's shafting us over it all, I still will not support criminals selling tobacco." Mr Cooper has tried to quit smoking many times but says the price of cigarettes has never been a motivating factor for him

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