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Last edited: 2026-06-16 By: iSmokeKing.se

It has been shown that cigarette smoke upregulates ACE2 in a dose-dependent manner in lung epithelium, including the goblet, club, Clara cells, and alveolar type 2 (AT2) cells of human and rodent lungs, and quitting smoking decreases ACE2 expression (reversible) [13]