Modulador de expresin gnica de amplio espectro : estudios transcriptmicos (Pickart et al., Biomed Res Int 2015) demuestran que GHK-Cu modula la expresin de ms de 4,000 genes humanos (15% del genoma codificante), reseteando perfiles transcripcionales hacia patrones de tejido joven
As peptide use has become more visible in fitness, sports performance, and research settings, many people want to know whether these compounds can appear on a drug test and under what circumstances they might be detected
Renshi Xu, orcid.org/0000-0003-0313-3434 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Abbreviations AD: Atopic dermatitis AMP: Anti-microbial peptides ATRA: All-trans-retinoic acid CGD: Chronic granulomatous disease COX: Cyclooxygenase CRH: Corticotrophin GLUT: Glucose transporters HBD: Human beta-defensins IgE: Immunoglobulin E IL: Interleukin iNOS: Inducible nitric oxide synthase IU: International unit LPO: Lipid peroxides MC: Mast cells NAD: Nicotinamide adenine dinucleotide NFB: Nuclear factor kappa B NK cells: Natural killer cells PARP-1: Poly-(ADP-ribose) polymerase-1 POMC: Proopiomelanocortin PTHrP: Parathyroid hormone-related protein RAR: Retinoic acid receptors RELM: Resistin-like molecule RETN: Resistin ROS: Reactive oxygen species SVCT: Sodium-dependent Vitamin C transporter TEWL: Trans-epidermal water loss TLR: Toll-like receptors TNF-: Tumor necrosis factor-alpha UHMWPE: Ultra-high molecular weight polyethene VDR: Vitamin D receptor References Kolarsick PAJ, Kolarsick MA, Goodwin C
