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Treating patients with positive antibodies who have otherwise normal thyroid function has NOT been proven to be of benefit Initially, the disease may cause toxicity ( Hashi-toxicity ) which can cause a transient hyperthyroidism after this the patient may become hypothyroid or euthyroid

To determine baseline infection in all groups, a few representative animals ( n = 3 per group) were sacrificed, followed by an evaluation of disease progression at indicated time points with animals ( n = 5) per group