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As interpreted by FDA in guidance, the phrase harmful and potentially harmful constituents (HPHCs) refers to any chemical or chemical compound in a tobacco product or in tobacco smoke that is, or potentially is, inhaled, ingested, or absorbed into the body, including as an aerosol (vapor) or any other emission

The authors grant HPHR permission to review and (if selected) publish this manuscript, and this manuscript is not under consideration by another publication and has not previously been published elsewhere

Perhaps differences between countries in drinking cultures (e.g., wet or dry cultures, Savic et al., 2016), attitudes toward alcohol use, patterns of risky alcohol consumption, drink sizes and strengths, and types of alcohol typically consumed (beer, wine, vs

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