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Influence on Neurotransmitter Systems Dysregulation: Nicotine affects neurotransmitter systems, such as the cholinergic system, which plays a role in seizure activity

The previously mentioned UK randomized controlled trial showed that 80% of participants in the e-cigarette group continued to use e-cigarettes after 1 year of abstinence from smoking, while only 9% of participants in the NRT group continued to use NRT after 1 year.[22] For smokers of combustible cigarettes, another possible beneficial aspect is harm reduction via partial substitution of combustible cigarettes with e-cigarettes

I did it once in my vein

With up to 1,650 CFM airflow, it pulls in contaminated air, filters it, and recirculates cleaner air back into the room