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The ROS is a single summary of the effect of smoking on the outcome, with higher positive ROSs corresponding to stronger and more consistent evidence and a higher average effect size of smoking and a negative ROS, suggesting that, based on the available evidence, there is no significant effect of smoking on the outcome after accounting for between-study heterogeneity

Although Cristopher Columbus brought with him a few tobacco leaves and seeds back to Europe, most Europeans didn't get their first taste of the plant until the mid-16th century, when adventurers and diplomats like France's Jean Nicot for whom nicotine is named began to popularize its use

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My body, for example, immediately responds in the presence of cigarette smoke ( xing yn yn w )