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International Smuggling and Counterfeiting Hurts Americans Smuggling that occurs within the borders of the United States is mostly a zero-sum activity from a cost perspective, and smugglers may even facilitate an increase in total economic activity by decreasing the market tax burden, albeit at unacceptably high social costs (not to mention the innate criminal nature of the activity)

Perceived risks and benefits and frequency of cannabis use among people with HIV in different legal environments

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However, a meta-analysis of 15 studies found that even a single THC administration induces depression and anxiety with large effect sizes (Hindley et al