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The frequency of smoking was similar across countries

The models were first conducted while selecting only days where estimated BAC was 110 mg/dl or more to eliminate data from days when hangover was unlikely to occur, and then, for comparison, repeated while selecting days of any lighter drinking (because nondrinking days are irrelevant)

The carcinogens cause direct damage to the DNA of bladder cells by forming DNA adducts, which disrupt essential genes responsible for cell repair and regulation, such as TP53