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Med Clin North Am 107(5):793805

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Historical context around electronic inhalable nicotine products NVPs were first patented in 2003 and over the ensuing decade became major players in many nicotine markets.7 Technological innovations in the mid-to-late 2010s sparked considerable increases in NVP popularity, among not only current and former adult cigarette smokers8 but also youth and young adults in a handful of Western countries.9 10 This fast-paced evolution has transformed NVPs into an expansive product category encompassing devices of all shapes, sizes and user modifiability,11 in addition to thousands of unique flavours added to nicotine solutions.12 NVP devices and nicotine solutions are manufactured by multinational corporations and independent companies