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Some studies from the 1990s found that when people stop smoking, depressive symptoms such as suicidal tendencies or actual depression may result, [199] [218] although a recent international study comparing smokers who had stopped for 3 months with continuing smokers found that stopping smoking did not appear to increase anxiety or depression

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In 2012, 13 tobacco companies submitted recommendations to be included in the GMP regulations and subsequently met with FDA to review their recommendations and approach to developing them

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