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How Nicotine and Tobacco Affect Your Heart Hunterdon Vascular Care Cigarette Smoking, Cessation, and Risk of Heart Failure With Preserved and Reduced Ejection Fraction ScienceDirect DYK? Smoking is a major cause of cardiovascular diseases, which are diseases of the heart and blood vessels and includes coronary heart disease. Coronary heart disease can cause chest pain, heart attack Smoking: A Direct Hit to the Heart Every puff of a cigarette is a direct challenge to your cardiovascular system. Beyond the lungs, the chemicals in tobacco smoke enter your bloodstream
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