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It hoped to turn the River District into a place where customers could gather and explore food and entertainment venues without having to stop at barriers to finish a beer, glass of wine, or cocktail

The researchers combined an overnight sleep study known as polysomnography, which measures brain activity, breathing, heart rate, oxygen levels and other bodily functions during sleep, with parental questionnaires and urine tests measuring cotinine, a nicotine byproduct that serves as an objective marker of tobacco smoke exposure

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The switch is not a treatment for substance use disorders, she said, but rather just switching the use to a potentially less harmful form