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But if they cannot quit smoking combustible cigarettes, they should consider using novel nicotine products to either quit smoking altogether or to reduce their harm by transitioning fully to these products. Going forward, work needs to be done to better understand the non-cancer risks associated with e-cigarettes, such as respiratory and cardiovascular disease

Brody AL et al (2006) Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors

A main selling point of e-cigs is that they can be used anywhere, because they don't produce toxic smoke that puts others at risk

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