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Normally, inflammation is a protective response triggered by the immune system to heal injuries and fight off infections

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Finding that the vast majority of cases of oral cancer were caused not by the use of snuff or chewing tobacco but by smoking cigarettes, Rodu (now professor and endowed chair in tobacco harm reduction research at the Brown Cancer Center of the University of Louisville) proposed a public health strategy to encourage cigarette smokers to switch to moist snuff, which had been cleverly re-named smokeless tobacco [as in smoke less and no smoke] in the late-1970s by the United States Tobacco Company (UST), maker of the best-selling brands SKOAL and Copenhagen