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"We know that secondhand smoke contains thousands of irritating chemicals, and [we] suspect that they damage the immune system and lead to invasion by infectious agents," says Tammemagi

The Federal Register states, the FDA likewise has not approved any ENDS product for therapeutic delivery of any non-nicotine substance, including, in particular, CBD or other substances derived from marijuana. The Register added, Far from taking marketing claims of therapeutic benefit at face value, the FDA has undertaken enforcement action against companies making such claims about CBD and other cannabis-related products absent new drug approvals from the FDA. The USPS ruling concludes, that except for hemp-derived CBD containing no more than 0.3 percent THC by dry weight, cannabis and cannabis derivatives remain non-mailable under the Controlled Substances Act regardless of the POSECCA and notwithstanding any State or local laws on medical marijuana. How do I get an exemption to mail ENDS

In California, an evaluation of the states Tobacco 21 law found that the retailer violation rate [RVR] using youth decoys under age 18 decreased from 10.3% before the law was in effect to 5.7% afterwards