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Ozasa, K., Japan Collaborative Cohort Study for Evaluation of Cancer

For example, after 7 days of smoking Spectrum cigarettes, individuals given the low-nicotine content cigarettes significantly reduced the number of experimental cigarettes smoked compared to those given the high-nicotine content research cigarettes." Switching to VLNCCs caused substantial smoking reduction among ITS (non-daily intermittent smokers) but did not significantly increase abstinence

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