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A 600-puff pod or device at 20mg/ml is broadly comparable to around 20 cigarettes in nicotine content

A cigarette contains 12 mg of nicotine, and 1 to 3 mg of it is absorbed when smoking

"The dramatic spikes in youth e-cigarette use back in 2017 and 2018, primarily driven by JUUL, showed us how quickly e-cigarette sales and use patterns can change," said Deirdre Lawrence Kittner, director of the CDC's Office on Smoking and Health

But his office is in the region of the Tuscarora and Seneca tribal territories, where tobacco is also very big business, although the native manufacturers are mostly elsewhere particularly north of the border and at the Mohawk reservation