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Unintended Consequences of Cigarette Prohibition, Regulation, and Taxation. International Journal of Law, Crime and Justice 46 (2016): 6985

In reality, the direct exposure of certain areas of the mouth to tobacco increases the risk of severe health complications, which are not limited to the oral cavity but also extend to the esophagus, colon, pancreas, and bladder, due to the absorption and ingestion of tobacco juices, said Dr Jinan Mohammed Suleiman, a family physician at PHCC

The answer to whether you can use Lexapro and weed can also be found by looking at the health consequences of marijuana and the connection of marijuana to depression