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I think theyre pretty easy to understand. This last has sounded defensive

Thorax 60:794795 Clapp PW, Peden DB, Jaspers I (2020) E-cigarettes, vaping-related pulmonary illnesses, and asthma: a perspective from inhalation toxicologists

Tobacco's macrophage dysfunction directly impairs the pulmonary immune mechanism responsible for containing latent Mycobacterium tuberculosis allowing progression to active disease in people who would otherwise suppress the infection

This sequence of steps can then be reapplied at any time, which allows you to recreate the end result without having to go through each individual step every time