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Cotinine enhances the extinction of contextual fear memory and reduces anxiety after fear conditioning

The researchers found that a one-standard deviation (SD) increase in logodds of genetically predicted smoking initiation was associated with higher risk of advanced AMD (odds ratio, 1.26), while a one-SD increase in logodds of genetically predicted smoking cessation was associated with lower risk of advanced AMD (odds ratio, 0.66)

The way life insurance providers compensate for the additional risk of insuring smokers is simple: by slapping you with higher premiums