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1996 The Cigarette Papers Glantz S, Slade J, Bero L, Hanauer P, Barnes D

US Food and Drug Administration, Guidance for Industry and Food and Drug Administration Staff

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In the Karok economy, smoking was not practiced for pleasure but always for some definite end: as a part of the days routine, or as a rite prescribed by the tribal customs. During my field trips with school children, one will invariably ask, How can you smoke this tree tobacco if eating it will kill you? I tell them that eating the plant kills you within a few hours, whereas smoking it kills you slowly