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Nicotine, along with higher miR-124 expression, stimulates Th1 polarization, and lower miR124 expression stimulates Th2 polarization

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Step 4 | After 12 weeks Stop using QuickMist NICORETTE Gum Step 1 | Weeks 1 2 1020 pieces/day Step 2 | Weeks 3 - 4 815 pieces/day Step 3 | Month 2 410 pieces/day Step 4 | Month 3 25 pieces/day Step 5 | Month 4 - 6 1 piece if the urge to smoke returns NICORETTE Lozenge Step 1 | Weeks 16 815 lozenges/day Step 2 | Weeks 79 48 lozenges/day Step 3 | Weeks 1012 24 lozenges/day Step 4 | Week 1314 12 lozenges/day if you feel the urge to smoke NICORETTE Inhaler Step 1 | Weeks 1 12 A minimum of 6 cartridges to a maximum of 12 cartridges/day Step 2 | Weeks 13 - 24 Reduce the number of cartridges gradually