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However, does this mean that placing stimulating electrodes into a cerebellar region alters the activity within that region

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Therefore, TMD6 and TMD7 helices of TAS1R3 are integral to allosteric modulation of the sweet receptor, implicating them in TAS1R2 and TAS1R3 subunit interactions and indicating an important role for this structural region in the conformational changes involved in receptor activation

doi: 10.1016/j.cgh.2015.02.019 230 SugimotoKIkeyaKBambaSAndohAYamasakiHMitsuyamaKet al