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Based on the important signaling pathways in macrophages that contribute to MAC infection summarized previously, in this chapter, we propose HDTs with the potential to control MAC infection by improving antimycobacterial activity and modulating detrimental inflammation

Metabolites in HIV-associated neurocognitive disorders (HAND) were similar to those of age-associated cognitive decline in the absence of HIV with elevated neurotransmitters (glutamate, N-acetylaspartate), markers of glial activation (myo-inositol), and ketone bodies (beta-hydroxybutyric acid, 1,2-propanediol) 55