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Glutathione, on the other hand, reduces H 2 O 2 to H 2 O by providing additional electrons

Hypotheses 143, 110122

astrocytes are the principal inducers of BBB properties in these endothelial cells, by projecting 'glialfoot' on the capillaries

The catalytic mechanism of GSTZs differs from other GSTs in that GSH is initially conjugated to the cis double bond of maleylacetoacetate allowing the isomerisation reaction, before being eliminated in a second step allowing the formation of fumarylacetoacetate (Thom et al., 2001)