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In patients with autoimmune hypothyroidism, thyroid dysfunction might be induced by cytokine-mediated apoptosis of thyroid epithelial cells and infiltrating T lymphocytes may not directly be involved in thyrocyte cell death during Hashimoto' s thyroiditis

However, BSO+AUR significantly sensitized all cell lines tested to Erlotinib ( Figure 10 ) suggesting that BSO+AUR must be used in combination with EGFR inhibitors to achieve maximal chemo-sensitization