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As monotherapy, cagrilintide produced 11.8% weight loss in the Phase 3 REDEFINE 1 trial at 68 weeks with the 2.4 mg dose

Safety and regulatory status vary significantly

This event has been reported to occur in about 30% of patients receiving invasive image examinations and is strongly associated with a high risk of death, long hospital stays, and adverse outcomes such as a high risk of chronic kidney disease (Nash et al., 2002