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(1996) reported the analog was 1.5-2x more potent than equimolar IGF-1 in catabolic rat models, and broader pharmacology literature places it at roughly 3x potency overall

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Isorhapontigenin attenuates cardiac microvascular injury in diabetes via the inhibition of mitochondria-associated ferroptosis through prdx2-mfn2-acsl4 pathways

GHK-Cu has been characterized as producing broad effects on gene expression in dermal fibroblast models, with shifts observed across pathways including extracellular matrix remodeling, cellular proliferation, antioxidant response, and copper homeostasis