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The anti-tumor function of cisplatin, an intercalating agent, has been linked to its ability to crosslink with the purine bases on the DNA, causing DNA damage, interfering with DNA repair mechanisms, and subsequently inducing cell cycle arrest and apoptosis in cancer cells 46
History [edit] Nome's main claim to fame is a gold rush that happened at the turn to the twentieth century and caused the population to grow to over 20,000
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