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224,225,226 Additionally, Klotho enhances insulin sensitivity in peripheral tissues, including muscle and adipose tissue, and has neuroprotective functions through the modulation of neuronal signaling pathways

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Cancers 14 , 5721 (2022)

5), have shown splendid delivery potential in both vitro and vivo studies, enhancing drug permeability across the ocular barriers and prolonging the residence time in the eye [23, 129]