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If you have large, painful gallstones, your doctor may recommend surgery to remove your gallbladder

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However, it is commonly observed that the terminal ileal or perianal region is more susceptible to CD, resulting in a discontinuous type of transmural inflammation

These functional protective effects are consistent with metaproteomic findings in children with recent-onset T1D (188), where gut microbiota dysregulation (including reduced butyrate-producing taxa) correlates with -cell damage severity, supporting a clinical link between butyrate deficiency and T1D pathogenesis