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19.0 nM) complexes show that the 10,000-fold excess of unlabeled TCMC-PSMA in the radioactive tracer mixture does not significantly affect the receptor binding affinity compared to the non-radioactive tracer which was prepared in a 1:1 metal-ligand ratio (Figure 10)

doi: 10.1186/s13287-022-03145-y

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Our findings here differ from the recent report of the induction of c-MET overexpression by hypoxia (Pennacchietti et al, 2003), a cellular state that is conceivably more prominent within the tumour core than along the peripheral expanding tumour front juxtaposing the adjacent lung alveoli