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Notably, advancements in small molecule design have produced compounds that can cross the bloodbrain barrier and selectively accumulate in dysfunctional mitochondria within affected neurons [87]

Analysis of three studies (totaling 109 participants) demonstrated consistent improvements in alanine transaminase (ALT) levels and reductions in oxidative stress markers like 8-hydroxy-2-deoxyguanosine (8-OHdG)