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Description

L-Carnitine and acylcarnitines: mitochondrial biomarkers for precision medicine

Bain MA, Faull R, Fornasini G, Milne RW, Evans AM

Basis for drug therapy and side effects prediction

Even though the 3D structure of OCTN2 is still not known, the molecular determinants for substrate specificity have been revealed: one ammonium and one carboxylate groups are strictly required for transport, while the distance between them is not important (Ohashi et al., 2002