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Brumas, V., Alliey, N

Retrograde trafficking of SORLA requires the multimeric adaptor complex retromer that binds to the FANSHY motif of the SORLA C-terminal tail [12, 13], whereas the anterograde trafficking of SORLA involves GGA1/2 [14, 15]

The presence of oxidized lipid species were detected in pravastatin group but protein oxidation markers (carbonyl and SH- groups) were not altered

This allows the nano-vesicles to absorb directly through the intestinal wall via the lymphatic system, achieving unrivaled intracellular nutrient delivery