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TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein

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The genome datasets used in this study was BDGP6.22 for RNAseq analysis the guts of young or old flies upon 24 hr Met restriction, BDGP6 for 3 RNAseq analysis of guts after 6 hours, 2 weeks, or 4 weeks of Met restriction, BDGP6.28 for single-cell transcriptome analysis

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