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HGF is a pleiotropic factor produced by mesenchymal cells in the stroma and as such is widely distributed in the extracellular matrix (ECM) of most tissues [1, 8]

J Pharm Sci 93:13671373 Yang B, Good D, Mosaiab T (2020) Significance of LL-37 on immunomodulation and disease outcome Yang Y, Chen H-Y, Hao H, Wang K-J (2022) The anticancer activity conferred by the mud crab antimicrobial peptide scyreprocin through apoptosis and membrane disruption

Mechanically, chronic hypoxia promoted the transcriptional expression of Acer2 by activating HIF-2

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