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Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate

The different mechanisms of action theoretically could be complementary, but without clinical studies, such combinations represent unknown risks that most healthcare providers wouldn't recommend

In: Berliner LJ, Parinandi NL, editors

Consistent with this, lactase activity largely depends on postconceptional age, while sucrase and maltase activities depend on combinations of postnatal age, environment and diet