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The Centers for Medicare and Medicaid Services and the National Center for Health Statistics provide guidelines for coding and reporting using the International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM)

This was calculated by first normalizing both metrics to the mean value within the ROI of interest of the control group, and then averaging both normalized metrics: where RID f , OD f, and AP f are, respectively the RID, the OD, and the AP within the ROI for the frame being studied, and OD Cont and AP Cont are the mean OD and the mean AP of the control group within the ROI