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As no data are available on efficacy of this formulation, we studied vitamin B12 serum levels, the physical activity scale of the RAND-36, the number of steps on an activity meter, and the fatigue and concentration scales of the CIS20r questionnaires, before and after 3 months of treatment in ME/CFS patients

Sources of B12 Vitamin B12 can be found in a wide variety of animal products, such as meat, fish, poultry, eggs, milk, yogurt, cheese and fortified foods such as breakfast cereal

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But medically, dark brown urine could be an alert that the liver or kidneys are malfunctioning particularly if the patient also has pale stools and yellowing skin and eyes